Your hypothalamus and adrenal glands abruptly and
excessive convert dopamine into norepinephrine upon stimulation.
The excessive norepinephrine elevation triggers cytockines and COX-2 to release
prostaglandin E2 in your vaginal, cervical and uterine tissues.
Prostaglandin E2 disables the vaginal, cervical and uterine neuroimmunity for
sperms to survive, to assist a sperm to fertilize an egg, and to further let
the fertilized egg implant into the uterine line. However, excessive
prostaglandin E2 causes burning sensation for the vulva, urethra and vagina even
without penile penetration.
The vagina-penetrated penis will become burning when the penis and urethra are
soaked in the vaginal fluid, although the male seminal vesicles, prostate and
bulbourethral glands are also producing a lot of prostaglandins (E1, E2, E3,,,,)
to help sperms to survive through the urethral tract.
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