Why androstenedione helps this middle-age last whatever he wants for more sexual orgasm?

Reader: 11/24/2003>
i've taken androstenediol on and off in cycles. i've noticed that when off, like now, i tend to ejaculate quickly, within a few minutes. it is a strong urge that i seemingly can not resist. when on cycle and taking androstenediol i seem to have more ejaculatory control and can continue to make love for as long as i want. often we stop when my partner is satisfied and tired. is there anything to this? do you have any solution?

thanks,

Dr. Lin: 11/25/2003> This tells your testosterone level is too low to super the parasympathetic nervous function and to produce a high quality semen with a high level of Prostaglandin E-1 without androstenedione. An optimal androstenedione and testosterone level can help stop the over-expression of prostaglandin enzyme COX-2 (CycloOXygenease-2) which produces excessive prostaglandin E-2 responsible for inflammatory (pains or cramps) in various tissue and organ systems; instead, it helps COX-1 for more prostaglandin E-1 (PGE-1) to relax and repair the muscle, nerve and joint. PGE-1 makes your erection last longer. Penile injection of PGE-1 can make the penis erection for several hours to several days. leading to priapism (persistent erection) - http://action.love/cases/case10363.htm and http://action.love/cases/case9800.htm
The most common problem for the middle-age men is a weak erection resulting in premature ejaculation.
A last-long erection requires a continuous recharge of the parasympathetic nervous function for the acetylcholine =>NO (nitric oxide) => cGMP (arterial dilator) and a continuous synthesis of Prostaglandin E-1 (PGE-1) in the penile spongy tissue to relax the arteries and nervous fire for penile expansion without invoking the Prostate and PC muscle contraction excises that stimulate the discharge of precum from the bulburethral glands located between the prostate and PC muscle. Your prostate tissue also requires a high level of PGE-1 to help the prostate's parasympathetic nerve keep the ejaculation duct and valve shut. A high quality of semen can help in this regard.
Generally, a testosterone level of 600-900 ng/dl will give you a best performance.
If your testosterone is low, you have to use the PC muscle and Prostate contraction to assist your erection and you also worry about your penis to go limp in a short. As a result, you will suffer from sexual stress and anxiety for sympathetic Fight or Flight where Fight = "Premature Ejaculation" and Flight = "Erection Withdrawal'. This is the typical middle-age and senior men's problem.
If your testosterone is too high, your prostate will be over-excited by the androgen hormones testosterone and DHT to ejaculate. Generally, after the parasympathetic nervous system is fully recharged by the androgen hormones, the sympathetic nervous recharge system will take over the turn and the seminal/sperm production will be up-regulated. This leads to ejaculation urgency when the seminal vesicles are fully. This is the typical healthy young men's premature ejaculation problem. On the other hand, a high testosterone level with a low serotonin level will turn the sympathetic nervous recharge system for Fight or Flight, even without having the parasympathetic nervous system recharged. This happens to chronic over-masturbators and drug abusers, who generally have a low serotonin level in brain and a weak serotonin modulation in the sympathetic nervous function. Note that over-masturbators and drug abusers may have their testicular function destroyed in he first place.

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