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![]() Reader : 5/20/2004> hello i'm not sure whether you remember me i was inquiring about reddish brown vaginal discharge. well that has past but i have still not started my period and this was about 1-2 weeks ago. could their be any sort of problems occuring? thank you for your time. helen. Dr. Lin: 5/20/2004> The reddish vaginal discharge is due to the frequent separation of your ultra-tinning uterine lining due to an extremely low progesterone level. It is likely a peri-menopause symptom. Obviously, your hypothalamus/pituitary-ovarian axis has been shut down or weakening enough to disable your ovarian function. The following factors can make it happen: if you experience premature menopause (genetic factors) or excessive stress, were on hormone-based birth control before, abused drugs before, or has chronically used a vibrator. The most common one is due to hormone-based birth control and a chronic excessive stress. Generally, a high dose of Progestin in the birth control pills or shot can cause a long-term shutdown of the ovarian function after the progesterone receptors and dopamine nerves in the hypothalamus/pituitary gland are taken over and disabled, respectively, by Progestin. If the liver enzymes fail to detoxify Progestin into progesterone, your liver P450 detoxification system becomes too exhausted to support the neurotransmitters synthesis and the cholesterol - androgen hormone conversion, your ovarian function is shut down, and progesterone for maintaining your uterine lining thickness is not available. Thus, your uterus can be constantly bleeding, but won't have a menstrual cycle driven by the variation of the pituitary LH and FSH. An excessive stress can cause infertility. TExcessive stress causes an excessive dopamine-adrenaline conversion for the sympathetic nervous fight or flight. In addition to stiff-muscle/joint or PMS pains or cramps due to a blockage of the prostaglandin E-1 synthesis and an over-expression of COX-2 for prostaglandin E-2 production by an excessive adrenalin level in the bloodstream, this will cause an deficiency of dopamine in the hypothalamus/pituitary receptors and then shut down or disturb the pituitary-ovarian axis. |
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