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![]() Reader: 12/11/2005>i have pains in my testicles and i also experience pains after ejaculation and atimes i get watery semen i looked through your site though i am tired now i jsut need to know what to do to restore me. I know it is due to over mastubation infact i try to ejaculate again too quikly. But i want no drugs in fact i cannot afford them but apart from that i still feel suspicious all i need is assistane with foods and fruits that i should use and heatlh habits i should develope and exercises. Also what is the chikong breathing and anal breathing methods. Please assist me i have not even started a sex life with girls and now this i need your assistance. also after this how can i naturally enlarge my penis reply me soon with solutions. Thanks for your help Dr. Lin: 12/11/2005> Your problem is due to exhaustion of your adrenal and testicular function, leading to over-production of prostaglandin E-2 which is supposed to stimulate your testicular function in conjunction with the epinephrine action on the beta receptors in the testis. When your adrenal medulla release excessive epinephrine before, during or after ejaculation to act on the the sympathetic nervous alpha receptors for arterial constriction and when your androgen hormones testosterone or/and DHT level is too low to modulate the COX-2 gene expression, prostaglandin E-2 becomes over-produced for pains or cramps. When epinephrine is bounded into the alpha receptors and COX-1 is under expression due to a lack of hormones DHEA/testosterone/DHT/Oxytocin and parasympathetic/serotonin nervous action, the prostaglandin E-1 production is shut down and the tissue and nerves lose its elasticity and flexibility for persistent pains and cramps. Prostaglandin E-2, prostaglandin E-1 and the androgen hormones forms a homeostatic feedback control in the local testicle tissues, where Prostaglandin E-1 is responsible for housekeeping, arterial dilation and erection for more blood flow to come into the issue. Over-ejaculation or masturbation broke your homeostatic feedback control in your testis. The same condition is also applied to the other tissue and nerves associated with the balance of prostaglandins E-1 and E-2 although prostaglandin E-2 won't stimulate the mass testosterone and DHT production there, except the brain and adrenal glands. In the prostaglandins pathways of the male reproduction organs, , COX-1
activities (for prostaglandin E-1 production) are located in the Leydig celles of the testis , in the epthelial cells of the caput, corpus and causda epindidymis, vas deferens, prostate and seminal vesicles, while COX-2's (for prostaglandin E-2 production) are supposed to be in the epthelial cells of the distal causda epindidymis, Leydig progenitors cells, vas deferens, prostate, and seminal vesicles. COX-1 displays the characteristics of a housekeeper gene, while COX-2 plays an stimulating
(imflammatory/active/warning) role in the physiological function. In the normal conditions, COX-2 expression are barely detective. Once the epinephrine and prolactin level shot up or/and the
parasympathetic and serotonin nervous function and the DHT level drops, COX-2 expression override COX-1 to sound off the alarm with its excessive prostaglandin E-2 production, in an attempt to stimulate the pituitary and testicular function for more oxytocin and DHT release, and slow down the adrenal medulla function for less epinephrine and more cortisone release. Thus, Excessive prostaglandin E-2 trigger your testicular pains and premature ejaculation. |
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