Chorea Huntington patient experiences Parkison's symptoms over one-week semen retention, but get depression after ejaculation.

Reader: 2/16/2009>Hi Dr. Lin,

I was diagnosed with Chorea Huntington (HD) some years ago. Today (I am 47) I show the normal symptoms for this dissease in the early stages. I do not take any medicin, no alcohol, no drugs, but I smoke cigaretts (20/day) which calms me.

One of the symtoms with HD is increased sexual activity. I am still married, my wife knows about my illness, she is 47 years old and I love my wonderful wife. I can seperate my orgasm from ejaculation and use this method regulary. When I do not have ejaculation for more than a week then my HD symptoms (trembling, shaking, ... ) get worse. When I have ejaculation I feel calm but depression gets into my brain. It seems that I have just to find the right ejaculation frequency for me, but are there any concerns regarding my illness? My doctors can or do not want to give my any advice how to handle sexuality. What are your suggestions for people suffering HD?

Excuse my bad English. Thank you for your answer in advance,

Dr. Lin: 2/16/2009>
When you retain your semen for certain time and practice orgasm without ejaculation, your dopamine, norepinephrine and epinephrine becomes too high.
A high level of norepinephrine and epinephrine can trigger excessive autonomic, sympathetic motoring nerves to act on your hands and feet for involuntary trembling and shaking when your cholinergic, serotonin and GABA nervous control are low despite of your high dopamine nervous function.
Sexual arousal generally elevate dopamine, acetylcholine, norepinephrine and epinephrine, but at the end, dopamine, acetylcholine, serotonin, GABA, norepinephrine and epinephrine will run low and some become too low, even if you don't ejaculate. It is like a roller coaster. After passing the peak, you will go down to the valley. When your cholinergic, serotonin and GABA nervous control in the valley and your norepinephrine/epinephrine/sympathetic nervous function are stronger enough to overpower your nervous controllers, you should expect mimic Parkison's symptoms or involuntary trembling and shaking. However, after ejaculating, your dopamine, cholinergic, serotonin and GABA nervous function and your testicular function are in the valley. You feel calm for a moment, followed by depression for couple days.
You should have a urinary analysis for your dopamine, acetylcholine, serotonin, GABA, norepinephrine and epinephrine.
I suggest you should increase the precursor of dopamine, acetylcholine, serotonin, and GABA 30-60 minutes before sexual encounter, so that the dopamine, acetylcholine, serotonin, and GABA nervous systems can drop down excessively after sex.

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