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![]() Case Study - Hyperthyroid, acetylcholine, erectile dysfunction and sexual orgasm Reader:2/24/2001> Ever since I had a case of viral induced hyperthyroid I have had a problem with premature ejaculation and difficulty maintaining erection. The thyroid problem started 3 years ago and was "gone" 2 1/2 years ago. More recently an endocronologist said the thyroid issue did not cause the other problems though I am still suspicious. While it seems unrelated, at the same time I started snoring loudly. Recently, an enzyme based herbal medicine has solved the snoring issue. Any ideas? Dr Lin: 2/24/2001> This summer, I have a chance to visit my youngest daughter's summer scientific program at the University of Florida, Gainesville. I have found a student finishing a research topic on the effect of Thyroid-Releasing Hormone (TRH) on the brain's acetylcholine level. Laboratory mice testing concludes that injecting a small amount of TRH can jump the brain's acetylcholine level in 10-fold with a hour! Here is your problem associated with hyperthyroid. The thyroid gland is part of the hypothalamic-pituitary-thyroid axis, and control of thyroid hormone secretion is exerted by
a negative feedback control loop. Thyroid-Releasing Hormone (TRH) relaesed by the hypothalamus stimulates the pituitary to release Thyroid-Stimulating Hormone (TSH)
which, in turn, stimulates thyroid hormone release. As thyroid hormone in the bloodstream increases, it negatively feedbacks to inhibit both TSH and TRH, leading to "shutdown" of thyroid epithelial cells. Later, when
the thyroid hormone level decreases, the negative feedback signal fades, and the thyroid wakes up again. Hyperthyroid produces excessive thyroid hormone
that deactivate your hypothalamus and pituitary, both of which are also the master controller of the brain (hypothalamic-pituitary)-adrenal/testicular
(ovarian) axis. That means, your DHEA and testosterone productions are slow too.
Perhaps, your
endocrinologist is a little out-of-date. It seems you are experiencing the midlife male menopause. |
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