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Case Study - Over-modulation of SSRIs antidepressants on the brain's and nervous functions for less seminal/lubrication production, erectile dysfunction and no sexual orgasm.
Reader: 11/2/2001>
I used to have a high sex drive and masturbated every day with multiple orgasms by practicing semen retention - I would ejaculate 2-3 times per week and make love with my wife once a week since she is not as interested as i am - then I started taking Celexa (an SSRI) for depression and a side effect is that I have lost almost all my sex drive - what is bothering me is that I can still have orgasms but only after a lot of work, and only once a week, but only if I also ejaculate - I have lost the ability to have waves of orgasmic feeling without ejaculating - do you have any ideas?

Dr. Lin: 11/3/2001> 

SSRIs antidepressants block the re-uptaking of serotonin in the brain as well as in the interneuron synapses in the spine which serotonin nerves modulate the the sympathetic nerves (CX Vagus and T10-L2) for orgasmic responses, and serotonin nerves modulate the parasympathetic nerves (S1-S5 and Co) for erection, urinary and bowel control. 
When the serotonin nerves overmodulates the parasympathetic nerves, the erection of penis, clitoris or G-spot becomes weak and evenly impotent.
When the serotonin nerves overmodulates the sympathetic nerves, sexual or orgasmic responses become weak and evenly disappear.
When the serotonin nerves overmodulates the brain's dopamine nerves, the hypothalamus/pituitary-testiscular (ovarian) functions become weak; the testosterone level and libido go low; seminal production or vaginal lubrication drops or dry out; erectile dysfunction or intercourse/oragasmic pains/cramps may occur. 
When the serotonin nerves overmodulates the brain's acetylcholine nerves, the hypothalamus/pituitary-adrenal functions goes low; DHEA production drops; the testosterone level and libido go low; seminal production or vaginal lubrication drops or dry out; erectile dysfunction or intercourse/oragasmic pains/cramps may occur, so do pains in the joints and muscles.

Serotonin is a neurotransmitter that modulates the other nervous activities.
You should observe the decrease of your ejaculation and its density.
You will start to experience erectile dysfunction soon.

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